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Breakthrough

ˈbreɪkθruː

Breakthrough definitions
noun
breakthrough breakthroughs
  1. a sudden, dramatic, and important discovery or development

    "a major breakthrough in DNA research"

    advance development step forward leap forward quantum leap step in the right direction success discovery find improvement innovation revolution
    • an instance of achieving success in a particular sphere or activity

      "his big breakthrough came in 1988 when he had two paintings accepted by the Academy"

  2. denoting a symptomatic case of a disease occurring despite preventative medication, vaccination, or prior infection

    "we're seeing more and more of these breakthrough infections"