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Irritate

ˈɪrɪteɪt

Irritate definitions
verb
irritate irritated irritates irritating
  1. make (someone) annoyed or a little angry

    "his tone irritated her"

    annoy vex make angry make cross anger exasperate bother irk gall pique put out displease get/put someone's back up antagonize get on someone's nerves rub up the wrong way try someone's patience ruffle ruffle someone's feathers make someone's hackles rise raise someone's hackles annoyed cross angry vexed exasperated irked piqued displeased put out fed up disgruntled in a bad mood in a temper testy in high dudgeon huffy in a huff resentful aggrieved
  2. cause inflammation or other discomfort in (a part of the body)

    "sprays and polishes can irritate dry, sensitive skin"

    • stimulate (an organism, cell, or organ) to produce an active response