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12-Letter Words Ending in IS

  • 143 words
  • All English dictionaries
  • Scrabble points
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Popular 12-Letter Words Ending in IS

The most familiar words on this list, with their Scrabble scores.

All 12-Letter Words Ending in IS 143 words

How common is IS at the end of twelve-letter words?

Our combined English word list has 143 twelve-letter words ending in IS. They average 18.4 points, the best is ZYGAPOPHYSIS (35 points) and P is the most common first letter (18.2%).

Total words
143
Average Scrabble score
18.4
out of 35 max
Everyday words
2%
common in ordinary English
Most common first letter
P
18.2% of words

Most common first letters

  • p 18.2%
  • a 9.8%
  • h 9.8%

Top vowel pairs

  • ia8.4%
  • ae7%
  • eu7%

Share of words where these two vowels sit side by side.

Rare words worth knowing

Valid in this dictionary but rarely seen in everyday English.

Highest-scoring twelve-letter word ending in IS

z 10y 4g 2a 1p 3o 1p 3h 4y 4s 1i 1s 1

Z 10 + Y 4 + G 2 + A 1 + P 3 + O 1 + P 3 + H 4 + Y 4 + S 1 + I 1 + S 1 = 35 points

Double word
70 pts
Triple word
105 pts

Face value of the tiles, then the whole word on a double- or triple-word square (letter bonuses and bingos not included).

zygapophysis

No dictionary definition on file. This is a valid game word that standard dictionaries rarely cover.

  • Scrabble US
  • Scrabble UK
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Five-letter lists built from the letters of yesterday's Wordle answer. The set changes every day.

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Why endings like IS matter

12-Letter Words Ending in IS by the numbers

12-Letter Words Ending in IS FAQ

How many twelve-letter words ending in IS are there?

There are 143 twelve-letter words ending in IS in our combined English word list. Other dictionaries give different totals, so switch dictionary at the top of the list to compare.

What is the highest-scoring twelve-letter word ending in IS?

ZYGAPOPHYSIS is worth 35 points in Scrabble before any bonus squares. Other strong options are BILHARZIASIS (26), BILHARZIOSIS (26), MORPHALLAXIS (26).

What are some common twelve-letter words ending in IS?

Everyday examples include TUBERCULOSIS, ELECTROLYSIS, APPENDICITIS, ENCEPHALITIS, MISDIAGNOSIS, OSTEOPOROSIS. Sort the list by "Most common" to see the familiar words first.

Which rare twelve-letter words ending in IS score well?

Uncommon but valid choices include BILHARZIOSIS (26), MORPHALLAXIS (26), HYPERKINESIS (24), PARAPOPHYSIS (24). Few players know them, so they can catch an opponent off guard.